March 2018 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Harnessing the Power of Mass Spectrometry in Biologics Discovery: Recent Developments and Future Directions
- Speaker:Guodong Chen, Bristol-Myers Squibb
- Date: Monday, March 12, 2018. 6:00 PM
- Please RSVP to XQiu2@ITS.JNJ.com by Thursday March 8.
- Time: Social Hour: 6:00 PM.
Talk: 7:00 PM.
- Place: Department of Chemistry, Villanova University (Mendel Hall 154)
Parking for the monthly meetings of the DVMSDG will change on a monthly basis due to heavy construction on campus over the next 1-2 years. Please check monthly for parking updates. The one-way access road to the Mendel Lot (S-3) from the Main Campus Gate on Ithan Avenue is now reopened. Please be aware this is a one-way street from the Connelly Center to the Mendel Lot. Evening classes will be going on during the other months and parking in Mendel may be limited.
1. To access the Mendel Lot off of Spring Mill Road, enter through the guard shack on Ithan Avenue and show your parking pass. If the Mendel lot is full, he main parking garage (I-1) is across Lancaster Avenue and the guards may direct you to park there.
2. When leaving, you MUST exit through the Mendel Lot gate. The gate will open automatically.
Since the introduction of the first recombinant DNA-derived protein insulin in the 1980s and the launch of Interferons and Interleukins in the 1990s, biologics market has shown a healthy growth. This is largely due to advances in recombinant DNA technology that have provided the means to produce therapeutic proteins. Mass spectrometry is uniquely positioned to cope with additional challenges for the analysis of biologics, due to its analytical sensitivity, speed and specificity. This presentation will present recent developments and future directions in mass spectrometry characterization of biologics, including primary structural analysis and higher order structure characterization in drug discovery.
Dr. Guodong Chen has extensive pharmaceutical research experience in major pharmaceutical companies, including Eli Lilly, Schering-Plough and Bristol-Myers Squibb. He is a Research Fellow heading analytical group at Bristol-Myers Squibb central New Jersey site. His matrix team leadership includes Biologics Program Leader. He has over 80 research publications in peer-reviewed journals and book chapters, three edited/co-edited books on pharmaceutical and biopharmaceutical analysis, multiple patents on antibody therapeutics and has given over 100 presentations at national/international conferences and academic institutes. His scientific contributions also include short course instructor at EAS, Pittcon and ASMS conferences, journal reviewer and session chair at various forums. He serves on the Editorial Board for Journal of the American Society for Mass Spectrometry. He received his Ph.D. in Analytical Chemistry from Purdue University under the direction of Professor R. Graham Cooks.
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