February 2002 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Proteomics and Mass Spectrometry in a Research and Clinical Setting."
- Speaker: Steve Seeholzer Fox Chase Cancer Center
- Date: Monday, February 11, 2002. 6:30 PM
- Time: Social Hour: Social Hour: 6:30 PM. (Pizza and Beer)
Talk: 7:30 PM.
- Place: Widener University, University Center Room C
- Abstract: Proteomics research has achieved an important status in broad areas of basic
and clinical research. This presentation will describe the evolving proteomics efforts at Fox Chase Cancer Center and elsewhere. I will present details of the technologies used, both hard and soft. Several observations will be highlighted to discuss issues arising from the complexity present in any given proteome. One focus of my presentation will be on quantitative aspects of proteome research.
- Bio: Dr. Seeholzer obtained his Ph.D. from the University of Pennsylvania where he studied carbon flow in cardiac metabolism using isotope labeling, NMR spectroscopy, and mathematical modeling. His post-doctoral career began
at Fox Chase Cancer Center studying protein structure and protein-protein interactions using multi-dimensional NMR spectroscopy. He continued there doing research in mechanistic enzymology. He has taught courses in Biochemistry and Advanced Cell Biology at the University of Pennsylvania and spent one year teaching high school chemistry. In 1996 he returned to Fox Chase Cancer Center to build a program in mass spectrometry and proteomics research. The pursuit of his interest in cell metabolism, protein structure, and mechanistic enzymology continue using mass spectrometry as a primary tool. His current proteomics efforts focus on early detection and risk assessment for breast cancer and on prevention of colorectal cancer.
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