September 2006 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Laser-induced Acoustic Desorption/Chemical Ionization Mass Spectrometry
- Speaker: : Professor Hilkka Kenttämaa, Department of Chemistry at Purdue University
- Date: Monday, September 11, 2006. 6:30 PM
- Time: Social Hour: 6:30 PM.
Talk: 7:30 PM.
Please RSVP to Scott Van Bramer email@example.com by Thursday September 7th.
- Place: Department of Chemistry, Villanova University (Room 154, Mendel Hall)
Mass spectrometry has an unparalleled power in chemical analysis due to its sensitivity, speed, ability to perform direct mixture analyses, and the variety of qualitative and quantitative information that can be obtained. However, the examination of nonvolatile analytes that are not easily ionized, e.g., saturated hydrocarbons, is still a challenge. Further, since analytes are usually ionized by proton transfer in MALDI and ESI, these analyses are limited to protonated and deprotonated analytes. In order to address these limitations, we have developed a mass spectrometric method that is based on separate and independent evaporation and ionization steps. The analyte is evaporated as intact neutral low-energy molecules into a Fourier-transform ion cyclotron resonance mass spectrometer (FT-ICR) by using laser-induced acoustic desorption (LIAD) from a thin titanium foil. Ionization of the neutral gas-phase analyte can be achieved in various ways, including chemical ionization (CI). The development of this methodology, as well as its application to the analysis of saturated hydrocarbon polymers and petroleum, and to fundamental studies of radical reactions of peptides and oligonucleotides, is presented.
Please send any comments, corrections, or suggestions to
This page has been accessed
times since 9/15 /96 .
Last Updated 8/15/2006