April 2008 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Fundamentals of 2D and 3D Ion Traps: Basic and Advanced Experiments
- Speaker: Gary L. Glish, Department of Chemistry, University of North Carolina
- Date: Monday, April 14, 2008. 6:30 PM
- Time: Social Hour: 6:30 PM.
Talk: 7:30 PM.
Please RSVP to Christopher Petucci PETUCCC@wyeth.com by Thursday April 10th.
- Place: Department of Chemistry, Villanova University (Room 115, Mendel Hall)
Over the last 20 years the 3D ion trap (more commonly called a quadrupole ion trap and sometimes a Paul or rf ion trap) has evolved from a GC detector to one of the most commonly used mass spectrometers. While important features of this mass spectrometer are the relatively low cost and ease of use, its popularity can be attributed to a very important performance characteristic - MS/MS efficiency. However, there are some limitations to the MS/MS experiment in ion traps. More recently a very closely related instrument, the linear (or 2D) ion trap has become popular. Most of the basic principles of operation are the same for the 3D and 2D ion traps, although one commercial version of the 2D ion trap has some important differences. This talk will provide an overview of the theory and operation of the 2D and 3D ion traps with an emphasis on the different operating/performance characteristics. Details of MS/MS experiments will be covered. Examples of different types of MS/MS experiments that can be performed in ion traps. - from an alphabet soup of acronyms: CID (RE, BAD, HASTE, PQD), IRMPD, ECD, ETD, I/M, I/I - will be presented.
Gary L. Glish received a B.A. from Wabash College in 1976 with majors in Chemistry and Economics. Deciding that he wanted to be able to do experiments to test hypotheses, he chose Chemistry over Economics for graduate school and obtained a Ph.D. from Purdue University (Advisor: R. Graham Cooks), in 1980. After receiving his Ph.D. Gary was a research scientist and group leader at Oak Ridge National Laboratory until 1992. In 1992 he took his current position on the faculty in the Department of Chemistry at the University of North Carolina.
Gary's research interests are in the areas of mass spectrometry instrumentation, ion activation, ion chemistry and development of methods for characterizing compounds of biological and environmental interest. In the area of instrumentation his focus has been on hybrid mass spectrometers and quadrupole ion traps. He has conceived and built several hybrid mass spectrometers including the first tandem quadrupole/time-of-flight mass spectrometer in 1984. He began his association with quadrupole ion traps in 1984 and more than half of his 100+ publications are related to quadrupole ion trap development and applications. He is a co-author of a book on tandem mass spectrometry and several book chapters on quadrupole ion traps.
Gary is active in the American Society for Mass Spectrometry. He was VP for Arrangements 1987-1989 and has chaired numerous interest groups and the Sanibel Conference twice. He served as an associate editor for JASMS from 1989-2007 and is currently VP for Programs/President-Elect. He co-teaches a short course at ASMS on Quadrupole Ion Traps. He was chair of the Lake Louise Workshop on Tandem Mass Spectrometry from 1999-2006.
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