May Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
Delaware Valley Mass Spectrometry Discussion Group Vendors Meeting.
Please RSVP to Bill Simonsick - William.J.Simonsick@USA.dupont.com - by Wednesday, May 5th, 2010.
An RSVP is needed to get a headcount for the served dinner.
ACS Philadelphia Section,
Critical Path Services,
Research Scientific Services,
Scientific Instrument Services,
- Topic: "Ultrahigh Mass Resolution and Mass Accuracy:
What's Possible, What's Not, and What It's Good For"
- Speaker:Alan Marshall
- Date: Monday May 10, 2010. 5:00 PM
5:00-6:30 p.m. Vendor Show (door prizes: American Express Gift Certificates)
6:30-7:30 p.m. Free Buffet-Style Dinner
7:30-7:40 p.m. Business (Election of Officers, etc
7:40-8:45 p.m. Talk (Alan Marshall )
- Please RSVP to Bill Simonsick by Wednesday, May 5th. An RSVP is needed to get a headcount for the served dinner
- (302) 999-3053
- Place: Villanova Conference Center (Note: this is NOT on the Villanova University campus).
Please note: If you are using a GPS locater, please enter 629 County Line Road, Radnor, PA 19087 or Latitude 40.05 and Longitude -75.35.
- Abstract: Mass measurement accuracy has recently improved substantially for several types of mass analyzers: notably Fourier transform (ion cyclotron resonance; orbitrap), and time-of-flight (reflectron). High mass resolution and mass accuracy form the foundation for various rapidly growing "-omics" fields (e.g., proteomics, lipidomics, glycomics, petroleomics, etc.). Moreover, access to high mass resolution and accuracy is becoming widespread--more than one of the above new instruments is being shipped per day. This talk will address: (a) what is (and what is not) possible from accurate mass measurement, (b) what determines mass accuracy, and (c) representative analytical and bioanalytical applications ranging from post-translational modifications of proteins to mapping of protein complexes to determine drug binding mechanisms. This work was supported by NIH (R01 GM78359), NSF Division of Materials Research through DMR-06-54118, and the State of Florida.
Marshall, A. G.; Hendrickson, C. L. "High-Resolution Mass Spectrometers," Ann. Rev. Anal. Chem. 2008, 1, 579-599.
Alan G. Marshall completed his B.A. degree with Honors in Chemistry at Northwestern U.in 1965, and his Ph.D. in Physical Chemistry from Stanford U. in 1970. He joined the Chemistry faculty at the University of British Columbia (Vancouver, Canada) in 1969. He moved to Ohio State University in 1980 as Professor of Chemistry and Biochemistry and Director of the Campus Chemical Instrument Center. In 1993, he moved to Florida State University, where he is Robert O. Lawton Professor of Chemistry and Biochemistry and Director of the Ion Cyclotron Resonance (ICR) Program, an NSF national user facility for mass spectrometry.
He co-invented and leads the continuing development of Fourier transform ICR mass spectrometry. His current reseach spans FT-ICR instrumentation development, fossil fuels and environmental analysis, and mapping the primary and higher-order structures of biological macromolecules and their complexes.
His major recognitions include: Fellow, American Physical Society; Fellow, American Association for the Advancement of Science; Fellow, Society for Applied Spectroscopy; three American Chemical Society national awards (Chemical Instrumentation, Field-Franklin Award, and Analytical Chemistry Award); two Spectroscopy Society of Pittsburgh Awards (Hasler Award and Spectroscopy Award); American Society for Mass Spectrometry Distinguished Contribution Award; International Society for Mass Spectrometry Thomson Medal; Chemical Pioneer Award from American Institute of Chemists, and Eni Frontiers in Hydrocarbon Research Award. He is a former President of the American Society for Mass Spectrometry, and serves on several editorial boards. He has published 4 books, 5 patents, and 500 refereed journal articles, and has presented more than 1,600 talks/posters at conferences, universities, government labs, and industry. His papers have been cited more than 18,500 times. Of his 109 former Ph.D.'s and postdocs, 32 have gone on to academic positions.
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