January 2015 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
Please note room change to Mendel Hall 115
- Topic: "Historical Perspectives and Future Considerations for Differential Mobility Spectrometry-MS"
- Speaker: Jim Glick, Novartis Institutes for BioMedical Research, East Hanover, NJ
- Date: Monday, January 12, 2015. 6:00 PM
- Time: Social Hour: 6:00 PM.
Talk: 7:00 PM.
Please RSVP to John Masucci JMasucci@its.jnj.com by Thursday January 8.
- Place: Department of Chemistry, Villanova University (Room 115, Mendel Hall)
- Abstract: Differential Mobility Spectrometry (DMS) emerged in the early 2000's as a compelling replacement to classical separation methods such as HPLC. It was envisioned that DMS could provide for the separation of complex mixtures on UPLC timescales with minimal sample preparation and low hardware capital costs. As with all emerging technologies, the promises of the technique and its practical application have not always been aligned. Over the last decade, details on the separation mechanism, separation efficiency and practical limits of DMS have emerged. This talk will review some of the early development efforts involving DMS technology and separation principals as well as highlight the current state-of-the-art of commercial DMS platforms.
For the past year, Jim has worked as a lab head providing LC-MS/MS support to pre-clinical project teams for both small and large molecule programs. Prior to his arrival at Novartis, Jim was the Director of the Barnett Institute's Core Mass Spectrometry facility at Northeastern University in Boston, MA. In this capacity, he provided small molecule and proteomics LC-MS/MS support to a wide variety of academic programs and institutions. He received his Ph.D. in 2008 at Northeastern in bioanalytical mass spectrometry under the direction of Professor Paul Vouros. It was during his time that Jim was exposed to the potential benefits of DMS and has worked to use this technology to support method development applications.
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