March 2015 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
Please note room change to Mendel Hall 115
- Topic: "Forensics, Metabolomics and Molecular Imaging by Mass Spectrometry"
- Speaker: Facundo M. Fernández, Georgia Institute of Technology
- Date: Monday, March 9, 2015. 6:00 PM
- Time: Social Hour: 6:00 PM.
Talk: 7:00 PM.
Please RSVP to John Masucci JMasucci@its.jnj.com by Thursday March 5.
- Place: Department of Chemistry, Villanova University (Room 115, Mendel Hall)
- Abstract: Mass Spectrometry (MS) is one of the key analytical methods used to identify and characterize small quantities of biological molecules embedded in complex matrices. Although MS has found widespread use, technical improvements in its instrumentation are needed to extend its application to the grand challenges that face the environmental, chemical and biomedical sciences. In this talk I will present insights into new approaches for generating ions under atmospheric pressure in an "open air" format followed by mass spectrometric detection. That research has enabled our group to perform a series of experiments in the fields of forensics, imaging and metabolomics. I will describe how "open air" MS has helped us detect the components in and track the sources of counterfeit drugs in developing countries, perform high throughput metabolic fingerprinting of patients with cancer, and image a variety of surfaces. I will also describe more fundamental work involving finite element simulations and Schlieren imaging of ion transport processes at the atmospheric pressure interface of the mass spectrometer. Finally, I will describe new results where plasma ion sources are used for better coupling of LC to MS.
Prof. Facundo M. Fernández was born in Buenos Aires, Argentina. He received his MSc in Chemistry from the College of Exact and Natural Sciences, Buenos Aires University in 1995 and his PhD in Analytical Chemistry from the same University, in 1999. In August 2000, he joined the research group of Prof. Richard N. Zare in the Department of Chemistry at Stanford University. His work focused on several aspects of Hadamard transform time-of-flight mass spectrometry with an emphasis on coupling this technique to capillary-format separation methods. In 2002, he joined the group of Prof. Vicki Wysocki in the Department of Chemistry at the University of Arizona, to develop novel tandem mass spectrometers for proteomics. In 2004 he joined the School of Chemistry and Biochemistry at the Georgia Institute of Technology where he is currently a Full Professor. He is the author of over 115 peer-reviewed publications and numerous presentations at international conferences. He has received various awards, including the NSF CAREER award, the CETL/BP Teaching award and the Ron A. Hites best paper award from the American Society for Mass Spectrometry, among others. His current research interests include the study and development of new methods and instrumentation in ion mobility and mass spectrometry for metabolomics, forensics, and imaging.
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