April 2017 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Open Access Preparative LCMS - Enabling Drug Discovery One Purification at a Time
- Speaker:Ann O'Brien, Incyte, Wilmington DE
- Date: Monday, April 10, 2017. 6:00 PM
- Please RSVP to firstname.lastname@example.org by Thursday April 6.
- Time: Social Hour: 6:00 PM.
Talk: 7:00 PM.
- Place: Department of Chemistry, Villanova University (Mendel Hall 154)
In the fast paced environment of pharmaceutical discovery chemistry, preparative purification should not be the bottleneck in delivering molecules and meeting program deadlines. Every molecule made by medicinal chemists has the potential to be the molecule that could saves lives. Molecular purity is essential in testing the hypothesis in which the molecule was designed. Open Access Preparative LCMS allows for high quality, efficient, on-demand purifications that medicinal chemists can perform themselves. The key to maintaining Open Access Prep LCMS is custom software, developed in-house, that simplifies the process of sample submission, LCMS method development, fraction collection and data interpretation. This presentation will detail the hardware and software that enables Open Access Preparative LCMS at Incyte Corporation.
Doctorate of Philosophy (PhD), Analytical Chemistry, University of Delaware, Newark, Delaware, 2007 - Dr. Murray Johnston
Bachelor of Science (BS), Chemistry, Sacred Heart University, Fairfield, Connecticut, May 2001
Senior Research Investigator- Incyte Corporation, Wilmington, DE, March 2016 to present
Senior Research Chemist- DuPont, Wilmington, DE, September 2011 to February 2016
Senior Research Chemist- Merck Research Labs, Merck & Co., Inc., West Point, PA, June 2007 to September 2011
Analytical Research Chemist, R.T. Vanderbilt Co. Inc., Norwalk, CT, June 2001-August 2002
Analytical Research Chemist, Unilever HPCUSA, Trumbull, CT, June 2000-June 2001
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