Delaware Valley Mass Spectrometry Discussion Group
September 1998 Meeting Announcement
- Topic: "Ion Trapping in a Quadrupole World"
- Speaker:Bill Herron. Structural Elucidation Team, DuPont Agricultural Products
- Date: Thursday, September 24, 1998
- Time: Social 7:30 p.m., Seminar 8:00 p.m.
- Place: Sanofi. 9 Great Valley Parkway, Malvern, Pa 19355(directions below).
- Abstract: Structural elucidation is playing an increasingly important role in the process of agricultural products discovery. Mass spectrometry, as just one of the analytical tools available, is experiencing nearly exponential growth in trying to meet these requirements. This is being driven by the need for more information about molecules of increasing complexity and the sudden availability of more powerful, user-friendly mass spectrometry instruments. The quadrupole ion trap instrumentation is certainly enjoying one such renaissance.
This talk will focus on the fundamental workings and capabilities of ion trapping devices, with examples to illustrate various applications. Ion/ion chemistry with be discussed to show multiple charge states determination. Collision induced dissociation and ion-ion chemistry will be combined to look at the structure of the A-Chain of Insulin, a model peptide. As with any technique, there are caveats! Several examples will be discussed in which there are potential differences between data from quadrupole and quadrupole ion trap instruments. Many of these differences can be overcome or even provide unique analytical information.
- Bio: Bill graduated in 1993 from State University of Buffalo at New York under Professor James F. Garvey. After a postdoctoral fellowship at Oak Ridge National Laboratory with Scott A. McLuckey and Douglas E. Goeringer, he worked as a physical chemist at General Electric Nuclear Fuels. Bill joined DuPont Agricultural Products in 1997.
- Directions: Sanofi Research. 9 Great Valley Parkway, Malvern, Pa 19355
- Maps
- From the Philadelphia International Airport:
- Take I-95 South to I-476 (the Blue Route)
- Take I-476 North to interchange 6 (I-76), the Schuylkill Expressway)
- Take I-76 West
- Take Exit 26B (West Chester) to Route 202 South
- Common Instructions.
- Take Route 202 South to Route 29 North (Great Valley/Malvern)
(Exit ramp becomes Liberty Blvd., which intersects Route 29 at a traffic light just past the Desmond Hotel. Turn Right on Route 29 North)
- Take Route 29 North to Great Valley Parkway (Second Intersection).
- Bear Right on jughandle to make a left turn onto Great Valley Parkway.
- Cross Route 29.
- Sanofi Research is the first building on the Right. Visitor Parking is marked.
- From Wilmington, DE:
- Take Route 202 North to Great Valley/ Route 29 Exit
- Turn Right on Route 29 North
- Pass Intersections of Route 29 with Swedesford Rd., Liberty Blvd, Valley Stream Pkwy.
- Turn Right on jug handle to make left turn on Great Valley Parkway
- Cross Route 29.
- Sanofi Research is the first building on the Right. Visitor Parking is marked.
- From Center City Philadelphia:
- Take Schuylkill Expressway (Route 76) West
- Follow 76 West / Valley Forge signs
- Take Exit 26B (West Chester) to Route 202 South
- (See common instructions.)
- From Pennsylvania Turnpike:
- Take Pennsylvania Turnpike to Valley Forge (Exit 24)
- Follow Signs to Route 202 South
- (See common instructions.)
- From New Jersey Parkway:
- Take NJTurnpike South to Pennsylvania Turnpike (Exit 6)
- Take Pennsylvania Turnpike to Valley Forge (Exit 24)
- Follow Signs to Route 202 South.
- (See common instructions.)
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- For More Information
Information:
Contact Bill Herron (302) 695-4654 WILLIAM.J.HERRON@usa.dupont.com
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Department of Chemistry
Widener University
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Last Updated Tuesday, September 15, 1998 4:00:37 PM