Delaware Valley Mass Spectrometry Discussion Group
November 1998 Meeting Announcement
- Topic: ""An Interdisciplinary Analytical Chemistry Approach to Streamline Pharmaceutical Development"
- Speaker: Dr. Larry M. Mallis, Wyeth-Ayerst Research
- Date: Thursday, November 12, 1998. 6:00 PM
- Time: Social Hour: 5:00 PM. 2nd floor Wilson Hall, 42nd & Woodland
Talk: 6:00 PM. Room 210, Griffith Hall
Dinner: 7:15 PM. cafeteria, 1st floor Wilson Hall
Dinner Cost - $18.00; students with ID and reservation, $9.00
Social hour only - $5.00; $3.00 students
The Board of Directors will meet at 4:00 PM in Room 201, Wilson Hall.
- RSVP. DINNER RESERVATIONS should be made by calling Mrs. Libby Harper at the Section Office, (215) 382-1589, by 5:00 PM on November 5th. Cancellations, if necessary, cannot be accepted after NOON on November 10th. UNCANCELLED RESERVATIONS WILL BE BILLED!
- Place:UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (former PCPS, Room 210, Griffith Hall,(directions below).
- Abstract:Traditional analytical chemistry departments are organized with respect to instrumentation or discipline. Thus many pharmaceutical companies possess analytical groups for HPLC, NMR, MS, etc. Typically the organic or medicinal chemist runs the analytical project by submitting his/her sample for analysis to each of the separate analytical groups. It has been observed that in this traditional environment, the speed, completeness, and sometimes accuracy with which a particular problem is solved is diminished. For example, often each analytical group will try to independently solve a structure elucidation problem without the influence/availability of another analytical technique. In this presentation, an interdisciplinary approach to analytical chemistry is presented. Along with specific examples of how this approach speeds up problem solving, this presentation will discuss ways in which the various stages of pharmaceutical development provide queues for the needs of the analytical department.
- Bio:Larry M. Mallis received his B.S. in chemistry from Cook College of Rutgers-the State University in New Brunswick, NJ and his Ph.D. in analytical chemistry from Texas A&M University, College Station, TX under D.H. Russell. At Wyeth-Ayerst Research he is involved in the analysis of discovery medicinal compounds using NMR, mass spectrometry, and analytical and preparative HPLC, etc. Research interests involve developing new methodologies for high-throughput, stability, and metabolic profiling of discovery compounds using LC/MS and LC/MS/MS techniques.
FREE PARKING is available in parking lots on either side of 43rd and Woodland; ample street parking is also available.
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Contact Bill Herron (302) 695-4654 WILLIAM.J.HERRON@usa.dupont.com
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