September 1999 Meeting Announcement, Delaware Valley Mass Spectrometry Discussion Group
- Topic: "Coupling High-Throughput with Mass Spectrometry, A Challenge for the Life Sciences?"
- Speaker: Stephen Martin, PE Biosystems
- Date: Monday, September 13, 1999. 7:00 PM
- Time: Social Hour: 7:00 PM.
Talk: 7:30 PM.
- Place: Merck, West Point, 37 Auditorium
Throughput. Independent of the specific biological field and/or application,
everyone wants to do more analysis per unit time. Pharmaceutical and
Biotechnology labs are being challenged to dramatically increase the number of
assays completed with their existing staffs and modest increases in the amount
of hardware. Laboratories that focus on mass spectrometric based assays are
looking to develop more integrated systems combining mass spectrometry and
related analytical techniques with robotics, software, LIMS and consumables to
provide this increase efficiency. The goal of developers of mass spectrometers
is to provide appropriate hardware, software and consumables that enable
increasing numbers of samples from electrospray and matrix assisted laser
desorption ionization per unit time while maintaining data integrity and
providing accurate reports based on these data. This presentation will review
some of the current applications in combinatorial chemistry, protein and DNA
analysis in which we are addressing these issues by implementing changes in
hardware, sample preparation and software. The outlook for future advances in
this area will also be addressed.
Director of Mass Spectrometry and Chromatography R&D within the Framingham
facility of PerSeptive Biosystems, a division of PE Biosystems. Steve has been
in this position since he joined PBIO in early 1994. This group develops
chromatography, MALDI and ESI TOF systems for applications in protein, DNA and
small molecules. Prior to that he was a scientist in the product development
group at Genetics Institute with a focus on the mass spectrometric
characterization of recombinant proteins. His background is in mass spectrometry
receiving his Ph.D. in 1984 at MIT under the direction of Prof.. Klaus Biemann.
His BS is in Chemistry from Boston University in 1980.
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