Instructor:Dr. Itzick Vatnick

Office :Kirkbride Hall 512

Telephone :Office: 4245Home:(302) 726?0977 no calls after 9:30 PM please

Office Hours:MW 10-12, F 11-12. I have an open door policy, please stop by at any time.

Text : Human Physiology.Vander, Sherman and Luciano. Eigth Edition

Class schedule         Lab schedule               Course requirements
 
 

OVERVIEW

This course in human physiology integrates the function of individual cells, organs, and systems into a cohesive and comprehensive explanation of the function of the human body. In the pasttwo decades rapid advances in molecular biology lead to an exponential increase in our knowledge of the cellular and molecular mechanisms that underlie the functions of organs and their coordination in other words humanphysiology. This course emphasizes the function of organ systems and their impact on the maintenance of homeostasis and body function as well as the cellular and molecular mechanisms underlying them.

The following syllabus is very tentative and only reflects my good intentions. Reality and you,will dictate the inevitable timing changes, additions and deletions. Changes will be announced in advanced in class (and/or will posted in the course web page).It is the policy of the Science Division policy is to include a statement about academic integrity in all science courses syllabi. You should be aware that the Science Division enforces the University's policy on cheating and other forms of academic fraud as described in the Student Handbook.

Process Objectives

At the end of each unit the student will be able to :

Cell physiology

1) Discuss the structure and function of cell membranes including transport mechanisms and their biochemical detail

2) Describe the electrochemical potentials of ions across membranes,explain and calculate resting potentials and ionic equilibra of the different ions

3) Describe the molecular structure of ion channels and cell membrane transporters and their regulation

4) Discuss and describe in detail cellular communication and its molecular basis

Excitable tissue

1) Describe the ionic basis for the generation of action potentials, its properties and coding function

2) Discuss in detail synaptic transmission

3) Give a general outline of the overall structureof the nervous system and describe the functionofeach component

4) Describe the function of the somatovisceral, and special senses sensory systems

5) Discuss in detail the structure function and pharmacology of the autonomic nervous system

6) Detail the structure and function of the central nervous system

7) Describe in detail the basic structure of skeletal muscle, the cellular and molecular processes ofcontractions and the mechanism involve in their regulation

8) Gain a basic understanding of biomechanics and muscle metabolism

7) Differentiate between the mechanism described above for skeletal muscle and those employed by cardiac and smooth muscle and describe in detail these mechanisms.

Endocrinology and whole body energetics

1) Describe in detail the classes of hormones and their cellular and molecular mechanisms of action

2) Relate the action of the endocrine system to the overall maintenance of homeostasis

3) Discuss in detail the structure and function of endocrine glands and hormones involved in the control of energy balance and thermoregulation

4) Explain the biochemical reactions summed up as totalmetabolism and calculate various parameters involved in energy and thermic balance (e.g. VO₂, C, HP)

Cardiovascular and respiratory systems

1) Discuss the function of the components of the vascular system and the control mechanisms that are responsible for the alteration of blood flow.

2) Describe the ionic and molecular basis for the electrical activity of the heart including basic electrocardiography

3) Discuss the structure of the heart in relation to its function as a pump

4) Discuss the electrical, contract ional and functional implications of the cardiac cycle

5) Describe the regulation andcalculate the various parameters of cardiac output

6) Describe and calculate the various parameters of hemodynamicsand their control mechanisms

7) Describe in detail the structure and function of the respiratory system

8) Calculate the various variables of ventilatory functionand discuss their controls

9) Calculate the various variables of the gas laws and relate them to the function of the respiratory system

10) Discuss the controls and mechanismswhich drive respiration and their cellular and biochemical detail

11) Discuss the mechanisms and controls of gas transport in blood

Kidney function

1) Describe the functional anatomy of the kidney

2) Outline the different assessment tools and calculate the various variables involve in the assessment of renal function

3) Describe in detail the physical, cellular and molecular processes involved in urine formation

4) Discuss the regulation of body fluid osmolarity and volume, electrolyte balance, and acid base balance.

Digestive function

1) Describe the functional anatomy of the digestive system

2) Relate the general controls of digestive function to the function of the various organs of the GI tract

3) Discuss the biochemical, cellular and molecular processes involved in digestion and absorption

4) Describe the hormones, their action and mechanisms of action, involved in the control of digestive function

5) Describe the autonomic and enteric innervations of the GI tract and relate their action to the control of motility and digestive processes of the GI tract